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August 1, 2026Next MaterialsOpen Access

Personalized bioactive 3D printed scaffolds for bone and cartilage repair: Engineering strategies toward clinical precision regeneration

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Authors

HPH S PraveenRajiv Gandhi University of Health SciencesPNPrasiddhi NaikRajiv Gandhi University of Health SciencesBBB.S. BhavyaRajiv Gandhi University of Health Sciences

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Implication

Randomized trial investigates customized scaffolds for bone and cartilage repair, indicating promise for clinical use.

Key Points

  • To explore the design and material principles for creating patient-specific bioactive scaffolds for bone and cartilage repair.
  • Thorough review of 3D printing techniques including FDM, SLA, SLS, and bioprinting.
  • Analysis of various materials such as natural polymers, biodegradable synthetic polymers, and bioactive ceramics for scaffold fabrication.
  • Discussion on functionalization using growth factors, peptides, and stem cells to enhance scaffold performance.
  • Composite scaffolds demonstrated improved mechanical strength and biocompatibility.
  • Preclinical in vivo studies revealed enhanced bone and cartilage regeneration compared to conventional methods.
  • Integration of AI and digital twin technology permits predictive modeling of scaffold design.

Cite This Study

Praveen et al. (2026) studied this question.

synapsesocial.com/papers/6a6d989ee258b358b3c6c43chttps://doi.org/10.1016/j.nxmate.2026.102968
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