What question did this study set out to answer?

To examine the relationship between malnutrition, serum amyloid A, and diabetic kidney disease (DKD) in type 2 diabetes patients.

February 13, 2026Clinical Laboratory0 citations

Serum Amyloid A, Malnutrition, Relative Hyperglycemia, and the Development of Diabetic Kidney Disease in Type 2 Diabetes

CNChung Nahm MLMoon Lee NFNoriyoshi FujiiUniversity of Tsukuba

Puntos clave

To examine the relationship between malnutrition, serum amyloid A, and diabetic kidney disease (DKD) in type 2 diabetes patients.
Analyzed the association between serum amyloid A, relative hyperglycemia, and DKD risk.
Focused on non-overweight patients with type 2 diabetes.
Compared levels of SAA, CRP, and HbA1c with DKD development.
SAA and relative hyperglycemia showed a stronger association with DKD risk than CRP and HbA1c.
Low nutritional status significantly contributes to DKD development in patients with type 2 diabetes.
Findings highlight the importance of monitoring nutritional status in diabetes management.

Resumen

Low nutritional status plays a crucial role in the development of DKD, possibly in connection with systemic inflammation, particularly in non-overweight patients with T2DM. SAA and SHR are more closely associated with DKD risk than CRP and HbA1c in patients with diabetes.

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