Case report describes Hutchinson's sign associated with ocular involvement risk, emphasizing the need for treatment.
A patient initially presents with an abnormal sensation on the tip of her nose, followed by the appearance of a localized redness and oedematous macule progressively evolving into a necrotic lesion at follow-up. This dermatological finding is known as the Hutchinson's Sign, a reactivation of the varicella-zoster virus along the nasociliary branch of the fifth cranial nerve. Hutchinson's sign can be associated with a risk of ocular involvement, and requires immediate systemic treatment. Ophthalmologic referral is recommended in cases of clinical suspicion of ocular globe involvement.
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Brodo et al. (2026) studied this question.
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