Thionaphthalimide-based photosensitizer for efficient photodynamic therapy

Qian Chen; Lingyu Jin; Jia Hong; Mingming Sun; Bo Yang; Yangjie Liu; Wen Xiu Ren; Qian‐Yong Cao

doi:10.1039/d6cc00184j

January 1, 2026Chemical Communications

Thionaphthalimide-based photosensitizer for efficient photodynamic therapy

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Key Points

The study aims to develop a thionaphthalimide-based photosensitizer for enhanced efficacy in photodynamic therapy.
Development of a novel amphiphilic photosensitizer
Evaluation of ROS generation in aggregated states
Mechanistic analysis of the photosensitizer's action
Demonstrated enhanced ROS generation compared to previous photosensitizers
Improved efficiency in photodynamic therapy applications

Implication

Demonstrates enhanced ROS generation for improved outcomes in photodynamic therapy, indicating potential for more effective treatments.

Abstract

A novel amphiphilic thionaphthalimide-based photosensitizer with enhanced ROS generation in aggregation stated has been developed for efficient photodynamic therapy.Scheme 1. Chemical structure of TNIS-TEG and its mechanism of action in...

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Cite This Study

Chen et al. (2026) studied this question.

synapsesocial.com/papers/699010df2ccff479cfe5727d https://doi.org/10.1039/d6cc00184j

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Thionaphthalimide-based photosensitizer for efficient photodynamic therapy

Key Points

Implication

Abstract

Discussion

Cite This Study

Thionaphthalimide-based photosensitizer for efficient photodynamic therapy

Key Points

Implication

Abstract

Discussion

Cite This Study

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