Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
February 14, 2026Journal of Hematology and Allied Sciences

Clinical heterogeneity of sickle cell disease in Indian subcontinent

View Full Paper
Ask AI
Bookmark
Share

Authors

KGK Ghosh

Discussion

Loading...

Member takes

Overview

This review analyzes the diverse clinical features of sickle cell disease in India, suggesting implications for treatment and understanding.

Key Points

  • The review aims to explore the varying clinical presentations of sickle cell disease across different regions in India.
  • Conducted a literature search in PubMed and Indian resources.
  • Reviewed original articles and conducted a retrospective analysis based on over 35 years of clinical experience.
  • Evaluated prevalence and severity of sickle cell disease across various Indian populations.
  • Sickle cell disease exhibits milder symptoms in India compared to Afro-Caribbean cases.
  • Increased severity noted in Nagpur compared to Gujarat and Maharashtra.
  • Milder cases often associated with high fetal hemoglobin and beta thalassemia co-inheritance.

Cite This Study

K Ghosh (2026) studied this question.

synapsesocial.com/papers/699011812ccff479cfe584afhttps://doi.org/10.25259/jhas_4_2026
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 3 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Newborn Screening for Sickle Cell Disease Among Tribal Populations in the States of Gujarat and Madhya Pradesh in India: Evaluation and Outcome Over 6 Years2022 · 22 citations
  2. 2The spatial epidemiology of sickle-cell anaemia in India2018 · 126 citations
  3. 3Genetic Variations in Bilirubin Metabolism Genes and Their Association with Unconjugated Hyperbilirubinemia in Adults2016 · 31 citations