What question did this study set out to answer?

Examine the link between comorbid anxiety and depression with cognitive impairment and dementia in older adults.

February 16, 2026BMC PsychiatryOpen Access

Association of comorbid depressive and anxiety symptoms with cognitive impairment and dementia in Chinese elderly people

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Authors

WZWenxuan ZhaoChinese Center For Disease Control and Prevention YLYuanxu LiuSichuan University LYLinming YueShandong First Medical University

Discussion

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Implication

Observational study finds cognitive impairment risk increases in older adults with comorbid anxiety and depression, indicating a need for early interventions.

Key Points

Examine the link between comorbid anxiety and depression with cognitive impairment and dementia in older adults.
Evaluated cognitive impairment using Mini-Mental State Examination (MMSE) and dementia via self/proxy-reported evaluations.
Assessed depressive and anxiety symptoms using CESD-10 and GAD-7 scales.
Analyzed the impact of comorbidity on cognitive outcomes using logistic and linear regression models.
Conducted a study in 13,792 adults aged 65 and older from the Chinese Longitudinal Healthy Longevity Survey.
7.7% of older adults had comorbid depressive and anxiety symptoms.
9.2% prevalence of cognitive impairment and 1.4% of dementia observed.
Comorbid symptoms linked to higher chances of cognitive impairment (adjusted OR: 2.07) and dementia (adjusted OR: 2.55).
Older women, especially those aged 80 and above, were at greater risk of comorbidity-associated dementia.

Cite This Study

Zhao et al. (2026) studied this question.

synapsesocial.com/papers/69926a620d0ce0adc9976a2c https://doi.org/10.1186/s12888-026-07883-8

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February 16, 2026BMC PsychiatryOpen Access

Association of comorbid depressive and anxiety symptoms with cognitive impairment and dementia in Chinese elderly people

View Full Paper

Ask AI

Bookmark

Authors

WZWenxuan ZhaoChinese Center For Disease Control and Prevention YLYuanxu LiuSichuan University LYLinming YueShandong First Medical University

Discussion

Member takes

Implication

Observational study finds cognitive impairment risk increases in older adults with comorbid anxiety and depression, indicating a need for early interventions.

Key Points

Examine the link between comorbid anxiety and depression with cognitive impairment and dementia in older adults.
Evaluated cognitive impairment using Mini-Mental State Examination (MMSE) and dementia via self/proxy-reported evaluations.
Assessed depressive and anxiety symptoms using CESD-10 and GAD-7 scales.
Analyzed the impact of comorbidity on cognitive outcomes using logistic and linear regression models.
Conducted a study in 13,792 adults aged 65 and older from the Chinese Longitudinal Healthy Longevity Survey.
7.7% of older adults had comorbid depressive and anxiety symptoms.
9.2% prevalence of cognitive impairment and 1.4% of dementia observed.
Comorbid symptoms linked to higher chances of cognitive impairment (adjusted OR: 2.07) and dementia (adjusted OR: 2.55).
Older women, especially those aged 80 and above, were at greater risk of comorbidity-associated dementia.

Cite This Study

Zhao et al. (2026) studied this question.

synapsesocial.com/papers/69926a620d0ce0adc9976a2c https://doi.org/10.1186/s12888-026-07883-8

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