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September 10, 2025Frontiers in PsychiatryOpen Access

Influence of comorbid anxiety and depression disorder on cognition in older adults with epilepsy

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Authors

HQHui QiuZWZongqin WangYWYanyan Wang

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Overview

Cross-sectional analysis reveals links between anxiety, depression, and cognitive impairment in older adults, highlighting the need for early intervention.

Key Points

  • Cognitive impairment was observed in 53.7% of older adults with epilepsy, emphasizing a significant health concern.
  • Those with depression had a cognitive impairment rate of 70.2%, compared to 51.0% without, indicating a strong association.
  • Multivariate linear regression identified significant correlations between cognitive impairment and symptoms of anxiety and depression.
  • Early screening for anxiety and depression may improve cognitive outcomes for older adults living with epilepsy.

Cite This Study

Qiu et al. (2025) studied this question.

synapsesocial.com/papers/68c1a40954b1d3bfb60de8adhttps://doi.org/10.3389/fpsyt.2025.1598767
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Cognitive impairment in older adults with epilepsy: a systematic review2026 · 1 citations
  2. 2Association of epilepsy with trajectory of depressive symptoms in late life: The Cardiovascular Health Study2025 · 3 citations
  3. 3Association of comorbid depressive and anxiety symptoms with cognitive impairment and dementia in Chinese elderly people2026
  4. 4Neuropsychiatric comorbidities in adult patients with new-onset epilepsy2024 · 1 citations
  5. 5Risk factor analysis and establishment of a predictive model for epilepsy comorbid with depression2025 · 1 citations