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This case report reveals a diagnosis of PCSM-TCLPD in a rapidly enlarging facial nodule, suggesting important implications for treatment decisions.
Primary cutaneous CD4+ small medium T-cell lymphoproliferative disorder (PCSM-TCLPD) is a rare, benign lymphoid proliferation that can clinically mimic malignant cutaneous neoplasms. This case report describes a rapidly enlarging, non-tender, pink nodule on the face of a 53-year-old female. Histopathology analysis revealed a diagnosis of PCSM-TCLPD. PCSM-TCLPD should be considered in the differential diagnosis of solitary facial nodules. Recognition of its characteristic dermoscopic and histopathological features can prevent unnecessary and aggressive treatment, as prognosis is excellent.
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Narula et al. (2026) studied this question.
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