What is the clinical evidence from this study?

Study design: Systematic Review. Population: Adults (≥18 years) with type 2 diabetes mellitus in low- and middle-income countries. Primary outcome: Pooled prevalence of diabetic cardiomyopathy diagnosed by cardiac imaging in adults with T2DM in LMICs.

February 16, 2026Systematic Reviews0 citationsOpen Access

Prevalence of diabetic cardiomyopathy in low- and middle-income countries: a systematic review protocol

AAA. ArowoloSouth African Medical Research Council LBL. D. M. BennieSouth African Medical Research Council WMW. Mahmoud

Key Result

This protocol aims to estimate the pooled prevalence of diabetic cardiomyopathy in adults with type 2 diabetes in low- and middle-income countries but does not report primary outcome results yet.

Key Points

The aim is to synthesize existing evidence on the prevalence of diabetic cardiomyopathy in low- and middle-income countries to understand its burden.
Conduct a systematic review of existing literature
Focus on studies reporting prevalence of diabetic cardiomyopathy
Target low- and middle-income countries
Expect to clarify the burden of diabetic cardiomyopathy in these regions
Aiming to gather data that will guide health system planning
Will inform future research and prevention efforts

Study Design

Type

Systematic Review

Structured PICO

Population

Adults (≥18 years old) with a confirmed diagnosis of type 2 diabetes mellitus (T2DM) in low- and middle-income countries (LMICs).

Outcome

Prevalence and distribution of diabetic cardiomyopathy (DbCM) in adults with T2DM in LMICs.

This systematic review protocol aims to synthesize available evidence on the prevalence of diabetic cardiomyopathy among adults with type 2 diabetes in low- and middle-income countries.

Limitations

Variability in diagnostic criteria affects comparability of prevalence estimates
Potential publication bias due to underrepresentation of studies with null or low prevalence
Limited diagnostic capacity in LMICs may lead to underestimation of DbCM prevalence

Abstract

By synthesising available evidence on the prevalence of DbCM in LMICs, this review will clarify the burden of disease and provide evidence to inform health system planning and guide future research and prevention efforts aimed at reducing diabetes-related heart failure.

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Cite This Study

Arowolo et al. (Sat,) conducted a systematic review in Adults (≥18 years) with type 2 diabetes mellitus in low- and middle-income countries. This protocol aims to estimate the pooled prevalence of diabetic cardiomyopathy in adults with type 2 diabetes in low- and middle-income countries but does not report primary outcome results yet.

synapsesocial.com/papers/6992b42c9b75e639e9b09149 https://doi.org/https://doi.org/10.1186/s13643-026-03117-w