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February 17, 2026Open Access

Minimally Invasive Versus Open Radical Antegrade Modular Pancreaticosplenectomy (RAMPS): A Multicenter Cohort Study on Surgical Radicality and Postoperative Outcomes

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Authors

LPLukas Heinrich PoelslerRBRuben BellottiNRNuh N. Rahbari

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Overview

Multicenter cohort study compares minimally invasive and open approaches for pancreatic surgery, suggesting similar outcomes.

Key Points

  • To compare the surgical radicality and postoperative outcomes of minimally invasive versus open RAMPS for pancreatic ductal adenocarcinoma.
  • Conducted a multicenter retrospective cohort study across three Austrian centers.
  • Included patients undergoing RAMPS for suspected malignant pancreatic lesions from 2016 to 2023.
  • Grouped patients by surgical approach: minimally invasive or open surgery.
  • R0 resection margin rates were 92.9% for MI and 85% for open surgery (p = 0.484).
  • Median lymph node yield was similar: 16 for MI versus 19 for open (p = 0.314).
  • Two-year overall survival rates were comparable: 71.6% for MI and 66.4% for open (p = 0.479).
  • No significant differences in postoperative complications were noted between approaches.

Cite This Study

Poelsler et al. (2026) studied this question.

synapsesocial.com/papers/6994055d4e9c9e835dfd6478https://doi.org/10.3390/cancers18040633
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Effect of minimally invasive or open radical antegrade modular pancreatosplenectomy on pancreatic cancer: a multicenter prospective propensity-score matched analysis2026
  2. 2Standard Distal Pancreatectomy Versus Radical Antegrade Modular Pancreatosplenectomy: A Systematic Review and Meta-Analysis of the Literature2026
  3. 3Radical antegrade modular pancreatosplenectomy <i>versus</i> conventional left pancreatectomy for pancreatic cancer: study protocol for the multicentre randomized clinical RAMPS trial2025
  4. 4Comparison of Survival Outcomes between Radical Antegrade Modular Pancreatosplenectomy and Conventional Distal Pancreatosplenectomy for Pancreatic Body and Tail Cancer: Korean Multicenter Propensity Score Match Analysis2024 · 2 citations
  5. 5Comparison of Survival Outcomes between Radical Antegrade Modular Pancreato-Splenectomy and Conventional Distal Pancreato-Splenectomy for Pancreatic Body and Tail Cancer: Korean Multicenter Propensity Score Match Analysis2024