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March 25, 2026International Journal of SurgeryOpen Access

Effect of minimally invasive or open radical antegrade modular pancreatosplenectomy on pancreatic cancer: a multicenter prospective propensity-score matched analysis

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Authors

MDMin DaiPLPengyu LiXTXiaodong Tian

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Overview

Multicenter analysis shows that minimally invasive surgery reduces hospital stay in patients with distal pancreatic cancer, suggesting effectiveness and safety.

Key Points

  • This analysis aims to compare the safety and effectiveness of minimally invasive and open radical antegrade modular pancreatosplenectomy in pancreatic cancer.
  • Multicenter propensity score matching study involving eight centers in China.
  • Included adults with resectable or borderline resectable distal pancreatic cancer who underwent MI or O-RAMPS.
  • Primary outcome measured was postoperative hospital stay, with secondary outcomes including R0 resection rates, complications, DFS, and OS.
  • In total, 232 patients were included (149 MI-RAMPS, 83 O-RAMPS).
  • MI-RAMPS resulted in a shorter postoperative hospital stay (median 9 days) compared to O-RAMPS (median 10 days, P = 0.005).
  • No significant differences were found in complication rates or oncological outcomes after propensity score matching.

Cite This Study

Dai et al. (2026) studied this question.

synapsesocial.com/papers/69c37be2b34aaaeb1a67ebdahttps://doi.org/10.1097/js9.0000000000005039
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Minimally Invasive Versus Open Radical Antegrade Modular Pancreaticosplenectomy (RAMPS): A Multicenter Cohort Study on Surgical Radicality and Postoperative Outcomes2026
  2. 2Comparison of Survival Outcomes between Radical Antegrade Modular Pancreatosplenectomy and Conventional Distal Pancreatosplenectomy for Pancreatic Body and Tail Cancer: Korean Multicenter Propensity Score Match Analysis2024 · 2 citations
  3. 3Comparison of Survival Outcomes between Radical Antegrade Modular Pancreato-Splenectomy and Conventional Distal Pancreato-Splenectomy for Pancreatic Body and Tail Cancer: Korean Multicenter Propensity Score Match Analysis2024
  4. 4Standard Distal Pancreatectomy Versus Radical Antegrade Modular Pancreatosplenectomy: A Systematic Review and Meta-Analysis of the Literature2026
  5. 5Radical antegrade modular pancreatosplenectomy <i>versus</i> conventional left pancreatectomy for pancreatic cancer: study protocol for the multicentre randomized clinical RAMPS trial2025