PulseExploreJournal ClubDebatesTrendingResearchersJournals
Instagram
HomeExploreJournal ClubTrending
Synapse
⌘+K
Synapse
February 19, 2026American journal of optometry and archives of American Academy of Optometry0 citations

Estimation of the in Vivo Oxygen Consumption Rate of the Human Corneal Epithelium

View Full Paper
MJMichael J. JaureguiAmerican Academy of OptometryIFIrving FattUniversity of California, Berkeley

Key Points

  • To estimate the oxygen consumption rate of the human corneal epithelium for understanding contact lens impacts on corneal metabolism.
  • Used a polarographic oxygen sensor for in vivo measurements on a human eye.
  • Conducted experiments at a temperature of 33°C.
  • Measured oxygen consumption across varying oxygen tensions.
  • Estimated oxygen consumption rate is 2.8 microliters per cm² per hour.
  • Rate remains constant between 620 mm Hg and about 20 mm Hg of oxygen tension.
  • Findings align with prior data from rabbit corneal epithelium.

Abstract

ABSTRACT Oxygen consumption rate of corneal epithelium must be known in order to estimate the effect of contact lenses conventional or hydrophilic on corneal metabolism. The in vivo measurements reported here were made with a polarograpbic oxygen sensor on a human eye. The oxygen consumption rate of the human corneal epithelium is estimated to be 2.8 microliters per cm 2 per hour at 33°C, in good agreement with previous data on rabbit corneal epithelium. The oxygen consumption rate is independent of oxygen tension from 620 mm Hg (80% O 2 ) down to about 20 mm Hg.

Ask AI
Helpful
Bookmark
Share
View Full Paper

Cite This Study

Jauregui et al. (1972) studied this question.

synapsesocial.com/papers/6996a768ecb39a600b3ed0ddhttps://doi.org/10.1002/j.2330-9474.1972.tb04344.x
Ask AI
Helpful
Bookmark
Share
View Full Paper