What question did this study set out to answer?

This study aims to evaluate the effectiveness of acupuncture in preventing chemotherapy-induced peripheral neuropathy (CIPN) in early-stage breast cancer patients.

February 19, 2026Clinical Cancer Research

Abstract PS1-01-12: Preventing Chemotherapy-Induced Peripheral Neuropathy with Acupuncture: Preliminary Results of a Pooled Analysis of Three Parallel Randomized Trials

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This study aims to evaluate the effectiveness of acupuncture in preventing chemotherapy-induced peripheral neuropathy (CIPN) in early-stage breast cancer patients.
Conducted a pooled analysis of three parallel randomized trials across the USA, China, and South Korea.
Included patients with stage I-III breast cancer scheduled for taxane-based chemotherapy.
Randomized participants to either acupuncture treatment or relaxation exercises with nature videos.
Acupuncture group received 14 sessions over 12 weeks, starting before the second chemotherapy cycle.
Primary endpoint was change in CIPN severity using the EORTC CIPN-20 sensory subscale.
128 patients were randomized with 63 in the acupuncture group and 64 in the control group.
Significant increase in mean sensory change scores in both arms at week 12.
No statistically significant differences between the acupuncture and control groups regarding CIPN severity.
Acupuncture was found to be safe and well-tolerated.

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Implication

Three parallel randomized trials evaluate acupuncture's effectiveness in preventing CIPN in early-stage breast cancer patients, suggesting further investigation is needed.

Cite This Study

Lu et al. (2026) studied this question.

synapsesocial.com/papers/6996a869ecb39a600b3ef1ca https://doi.org/10.1158/1557-3265.sabcs25-ps1-01-12

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Implication

Three parallel randomized trials evaluate acupuncture's effectiveness in preventing CIPN in early-stage breast cancer patients, suggesting further investigation is needed.

Abstract PS1-01-12: Preventing Chemotherapy-Induced Peripheral Neuropathy with Acupuncture: Preliminary Results of a Pooled Analysis of Three Parallel Randomized Trials

Key Points

Discussion

Implication

Cite This Study

Abstract PS1-01-12: Preventing Chemotherapy-Induced Peripheral Neuropathy with Acupuncture: Preliminary Results of a Pooled Analysis of Three Parallel Randomized Trials

Key Points

Discussion

Implication

Cite This Study

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