What question did this study set out to answer?

This study aims to determine whether acupuncture can further prevent the progression of chemotherapy-induced peripheral neuropathy in breast cancer patients already using cryotherapy.

February 19, 2026Clinical Cancer Research

Abstract PS1-01-02: Acupuncture for Preventing Progression of Taxane-Induced Peripheral Neuropathy (ATP) Beyond Cryotherapy: A Phase II Randomized, Double-Blinded, Sham-Controlled Trial

View Full Paper

Ask AI

Bookmark

This study aims to determine whether acupuncture can further prevent the progression of chemotherapy-induced peripheral neuropathy in breast cancer patients already using cryotherapy.
Randomized, double-blinded, sham-controlled trial design.
Participants received either real acupuncture or sham acupuncture weekly during chemotherapy.
Primary outcome measured was neuropathy pain using the Neuropathic Pain Scale after four weeks.
Secondary outcome assessed the relative dose intensity of chemotherapy administered.
Both real and sham acupuncture groups showed significant reductions in neuropathy pain after four weeks.
Retention rate was 28.8%, with no adverse events linked to acupuncture.
Relative dose intensity remained high, with 94% in both groups maintaining dosage thresholds.
Numerically, more real acupuncture patients experienced at least a 30% reduction in pain, though not significantly different from the sham group.

Discussion

No takes yet. Share an insight, caveat, or question.

Implication

This phase II trial evaluates acupuncture’s effectiveness in reducing neuropathy pain in early-stage breast cancer patients receiving taxane chemotherapy, suggesting potential benefits beyond...

Cite This Study

Zhi et al. (2026) studied this question.

synapsesocial.com/papers/6996a8b5ecb39a600b3efb99 https://doi.org/10.1158/1557-3265.sabcs25-ps1-01-02

View Full Paper

Ask AI

Bookmark

Implication

This phase II trial evaluates acupuncture’s effectiveness in reducing neuropathy pain in early-stage breast cancer patients receiving taxane chemotherapy, suggesting potential benefits beyond...

Abstract PS1-01-02: Acupuncture for Preventing Progression of Taxane-Induced Peripheral Neuropathy (ATP) Beyond Cryotherapy: A Phase II Randomized, Double-Blinded, Sham-Controlled Trial

Key Points

Discussion

Implication

Cite This Study

Abstract PS1-01-02: Acupuncture for Preventing Progression of Taxane-Induced Peripheral Neuropathy (ATP) Beyond Cryotherapy: A Phase II Randomized, Double-Blinded, Sham-Controlled Trial

Key Points

Discussion

Implication

Cite This Study

Keep reading

Keep reading