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The research aims to understand the dynamics and effects of transposable elements (TEs) in Drosophila virilis.

February 19, 2026Nucleic Acids ResearchOpen Access

Transposable elements as drivers of genome evolution in Drosophila virilis

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Explores TE dynamics influencing gene regulation and evolution in Drosophila virilis, suggesting a framework for understanding TE effects.

The research aims to understand the dynamics and effects of transposable elements (TEs) in Drosophila virilis.
Integrated multi-omics data
Identified 100 TE families
Conducted computational predictions and manual curation
Examined TE mobilization patterns and strain-specific expansions
Performed epigenetic profiling to study gene repression effects
Three temporal waves of TE mobilization identified: recent activity, speciation-associated, and ancient invasions
Evidence of horizontal transfer of TEs among D. virilis relatives
H3K9me3 from TEs represses adjacent genes in a distance-dependent manner
Discovery of a spontaneous polymorphic inversion linked to retrotransposons

Rezvykh et al. (2026) studied this question.

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Explores TE dynamics influencing gene regulation and evolution in Drosophila virilis, suggesting a framework for understanding TE effects.