Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
February 19, 2026Clinical Cancer Research

Abstract PS3-09-12: Thrombophilia Screening Prior to Tamoxifen Therapy in Early-Stage Hormone Receptor-Positive Breast Cancer: A Three-Year Retrospective Study

View Full Paper
Ask AI
Bookmark
Share

Authors

SGS. GkouraMetropolitan HospitalIBIoannis BinasHellenic Cooperative Oncology GroupEFE. Aravantinou - FatorouMetropolitan Hospital

Discussion

Loading...

Member takes

Implication

Retrospective analysis demonstrates modified treatment plans based on thrombophilia screening in patients, suggesting improved outcomes.

Key Points

  • To evaluate the significance of thrombophilia screening prior to initiating tamoxifen therapy in breast cancer patients.
  • Conducted a three-year retrospective analysis of breast cancer patient medical records.
  • Patients underwent thrombophilia screening before tamoxifen initiation.
  • Included hematological assessments to guide treatment modifications.
  • 31% of patients had clinically significant inherited thrombophilic factors.
  • 34% had high-risk acquired thrombophilic conditions.
  • 64% of patients had their treatment plans modified, including adjustments to tamoxifen regimens.

Cite This Study

Gkoura et al. (2026) studied this question.

synapsesocial.com/papers/6996a8b5ecb39a600b3efc2ahttps://doi.org/10.1158/1557-3265.sabcs25-ps3-09-12
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1The influence of tamoxifen in vivo on the main natural anticoagulants and fibrinolysis1993 · 47 citations
  2. 2Abstract PS1-01-07: Tamoxifen use increases endometrial cancer risk in premenopausal breast cancer patients2026
  3. 3Abstract PO5-11-08: Assessing practice patterns of antidepressant medication and tamoxifen use among patients with hormone receptor-positive breast cancer2024
  4. 4Tamoxifen treatment and risk of deep venous thrombosis and pulmonary embolism2009 · 187 citations
  5. 5Abstract PS3-01-18: Gene expression signatures of beneficial response to tamoxifen for breast cancer prevention2026