α-Functionalization of Ethers with Acridanes and Amines via Metal-Free Direct C(sp3)-H Radical-Radical Cross-Dehydrogenative Coupling

Key Points

• The aim is to develop a metal-free approach for functionalizing ethers using C(sp3)—H bonds with acridanes and amines.
• Utilized a radical-radical cross-dehydrogenative coupling technique
• Focused on unactivated C(sp3)—H bonds in ethers
• Conducted reactions with acridanes and amines
• Eliminated the need for metal catalysts
• Successfully achieved C9-etherification of various compounds
• Demonstrated high functional group compatibility
• Showed improved yields compared to traditional methods