PulseExploreJournal ClubDebatesTrendingResearchersJournals
Instagram
HomeExploreJournal ClubTrending
Synapse
⌘+K
Synapse
February 19, 2026Clinical Cancer Research0 citations

Clinical Characteristics and Survival of Pleomorphic Lobular Carcinoma Compared to ILC and IDC

Abstract PS4-08-10: Clinical characteristics and survival outcomes of Pleomorphic Lobular Carcinoma: a comparative analysis with classical ILC and IDC

View Full Paper

Authors

DWDavid WaljiVGVasily GiannakeasDLD. W. Lim

Discussion

Loading...

Member takes

Overview

Comparative analysis reveals pleomorphic lobular carcinoma has worse survival outcomes than ILC and IDC, indicating the need for focused research.

Key Points

  • This research aims to evaluate and compare survival outcomes for pleomorphic lobular carcinoma (PLC) against classical ILC and IDC.
  • Utilized the SEER database for patient identification.
  • Applied inverse probability of treatment weighting based on a multinomial propensity score.
  • Assessed covariate balance and evaluated survival using Kaplan-Meier curves.
  • Conducted LASSO regression to identify survival predictors.
  • Patients with PLC had larger and higher-grade tumors compared to those with IDC and ILC.
  • PLC had worse unadjusted overall survival (64.1%) and disease-specific survival (86.7%) compared to IDC and ILC.
  • Survival advantage for ILC versus PLC was significant at initial follow-ups, diminishing over time.
  • Larger tumors and advanced stage correlated with poorer outcomes in PLC patients.
Ask AI
Helpful
Bookmark
Share
View Full Paper

Cite This Study

Walji et al. (2026) studied this question.

synapsesocial.com/papers/6996a957ecb39a600b3f0481https://doi.org/10.1158/1557-3265.sabcs25-ps4-08-10
Ask AI
Helpful
Bookmark
Share
View Full Paper