Osteosarcomas are malignant neoplasms producing osteoid; approximately 5–7% occur in the jaws, often presenting in the fourth to fifth decades and exhibiting better prognosis than those in long bones. 1,2 We describe a 52-year-old female with a low-grade osteosarcoma of the right maxillary tuberosity, managed through national MDT input amid significant medical comorbidity. Clinical examination revealed a firm, ulcerated mass; biopsy and imaging initially suggested squamous cell carcinoma. Wide excision was performed. Specialist histopathology identified low-grade osteosarcoma. Postoperative MI precluded adjuvant therapy; annual surveillance was instituted. There is currently no clinical or radiologic evidence of recurrence. This case underscores the diagnostic complexity, need for MDT management, and surveillance importance in jaw osteosarcoma.
Smith et al. (2026) studied this question.