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Empirical evaluation demonstrates optimized denoising in fNIRS, indicating best practices for physiological signals.
Overall, our findings highlight the essential role of SC regression in recovering physiologically meaningful signals in fNIRS and recommend including all available SC channels within the GLM, coupled with orthogonalization techniques, as a generalizable best practice for denoising across hardware configurations.
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Lemaire et al. (2026) studied this question.
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