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Establishes a bioanalytical method to measure oligonucleotides in plasma, suggesting effective monitoring of therapies.
A simple and highly sensitive bioanalytical method for the determination of viltolarsen was established by optimizing RPLC and PPT, and the method was successfully applied to a phosphorodiamidate morpholino oligomers with a different sequence.
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Kameyama et al. (2026) studied this question.
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