Circadian-rhythm-based dynamics of the secretome in molecular subtypes of pancreatic ductal adenocarcinoma

Key Points

• This research aims to identify rhythmically regulated proteins in molecular subtypes of pancreatic ductal adenocarcinoma (PDAC).
• Conducted proteomics analysis using mass spectrometry.
• Examined secretome dynamics related to circadian rhythms.
• Leveraged data from the ProteomeXchange Consortium.
• Identified proteins that are rhythmically regulated in PDAC subtypes.
• Potentially established markers for future validation studies.