What question did this study set out to answer?

To evaluate the endocrine response to envenomation by snouted cobra or African puffadder in dogs.

Acute endocrine responses to snouted cobra ( Naja annulifera ) and African puffadder ( Bitis arietans ) envenomation in dogs

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Observational study reveals hormone responses and C-reactive protein correlation following snake bites in dogs.

To evaluate the endocrine response to envenomation by snouted cobra or African puffadder in dogs.
Prospective longitudinal observational study
Included 17 dogs envenomated by two snake species
Serum samples collected at multiple time points post-envenomation
Measured concentrations of TT4, thyrotropin, total cortisol, and CRP
Serum TT4 significantly lower in envenomated dogs compared to controls at all time points
TT4 concentrations negatively correlated with CRP levels
Puffadder and neurological cobra subgroup showed profound TT4 suppression until 36 h post-envenomation

Fourie-Viljoen et al. (2026) studied this question.

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