Continuous manufacturing of 3D-printed chewable pediatric gummies by coupling hot melt extrusion with direct extrusion additive manufacturing

Q: What does this research mean for the field?

3D printing can produce pediatric-friendly, chewable dosage forms with customized mechanical and sensory properties. Novelty: ClaimNovelty.NOVEL_FINDING. Consensus alignment: ConsensusAlignment.ESTABLISHES_NEW_DIRECTION.

Siva Satyanarayana Kolipaka; Laura A. Junqueira; Vivek Garg; Vivek Trivedi; Dennis Douroumis

doi:10.1080/17425247.2026.2636173

February 20, 2026Expert Opinion on Drug Delivery

Continuous manufacturing of 3D-printed chewable pediatric gummies by coupling hot melt extrusion with direct extrusion additive manufacturing

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Key Points

To develop chewable pediatric gummies using 3D printing techniques that enhance mechanical and sensory properties.
Utilized 3D printing technology for the production of gummies
Coupled hot melt extrusion with direct extrusion
Tailored formulation to meet pediatric requirements
Gummies exhibited improved mechanical properties
Enhanced dissolution profiles were achieved
Sensory attributes were optimized for better patient compliance

Implication

3D printing produces customized, chewable dosage forms in pediatrics, suggesting improved treatment adherence.

Abstract

3D printing enabled the production of pediatric-friendly, chewable dosage forms with tailored mechanical, dissolution, and sensory properties, supporting personalized medicine and enhanced patient compliance.

Discussion

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Cite This Study

Kolipaka et al. (2026) studied this question.

synapsesocial.com/papers/699bee1c1c6c6bad5397fcc0 https://doi.org/10.1080/17425247.2026.2636173

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Continuous manufacturing of 3D-printed chewable pediatric gummies by coupling hot melt extrusion with direct extrusion additive manufacturing

Key Points

Implication

Abstract

Discussion

Cite This Study

Continuous manufacturing of 3D-printed chewable pediatric gummies by coupling hot melt extrusion with direct extrusion additive manufacturing

Key Points

Implication

Abstract

Discussion

Cite This Study

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