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February 23, 2026Journal of Turkish Society of Obstetric and Gynecology0 citationsOpen Access

Inflammatory indices, machine learning and artificial intelligence in tubal ectopic pregnancy management

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UZUğurcan ZorluSDSenem Arda DüzGKGül Kurtaran

Key Points

  • This research aims to identify effective predictive biomarkers for managing tubal ectopic pregnancy (TEP) and evaluate machine learning applications.
  • Identified inflammatory indices, including AISI, SIRI, and FAR, as predictors of treatment failure.
  • Utilized machine learning models to enhance predictive accuracy.
  • Proposed a personalized approach to TEP management based on these findings.
  • AISI, SIRI, and FAR accurately predict methotrexate failure and the need for surgery.
  • Machine learning models significantly improve prediction effectiveness.
  • Results support the need for prospective validation before clinical application.

Abstract

AISI, SIRI, and FAR are strong predictors of MTX failure and surgical intervention in TEP. Combining these biomarkers with ML models markedly improves predictive performance and supports a personalized approach to TEP management. Multicenter prospective validation is needed before clinical application.

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Cite This Study

Zorlu et al. (2026) studied this question.

synapsesocial.com/papers/699bee1c1c6c6bad5397fd10https://doi.org/10.4274/tjod.galenos.2026.37165
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