Synthesis of Triazoloindazole Triones under Solvent-Free Condition using Cu(I) Coordinated to Vanillin-Isoniazid Supported Fe3O4/Silica Propyl as an Efficient and Magnetically Retrievable Nanocatalyst

Cu(I) coordinated to vanillin-isoniazid supported Fe3O4/silica propyl NPs were prepared and were analyzed by XRD, FT-IR, VSM, FE-SEM, TEM, and TGA-DTG. These nano catalysts were applied as an efficient and magnetically reusable nanocatalyst for the preparation of various derivatives of triazoloindazole triones and pyrazolyl-linked triazoloindazole triones under solvent-free condition. All of synthesized compounds were analyzed by NMR, FT-IR, and elemental analysis. This avenue offers many benefits such as productivity, fast reaction, and convenience for work and recovery. The catalyst is reusable for 8 runs by decantation using an efficient magnet without notable loss in activity.