Real-world findings show limitations of clinical assessments in evaluating treatment response in basal cell carcinoma, suggesting alternative monitoring methods.
In this real-world Chinese laBCC cohort, sonidegib produced a clinically meaningful response with a favorable safety profile. However, clinical and dermoscopic assessments showed substantial false positives due to posttreatment changes; pathological biopsy remains essential to confirm tumor clearance. Advanced noninvasive imaging (e.g., reflectance confocal microscopy) may further improve monitoring. Prospective studies with longer follow-up are warranted.
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Liu et al. (2026) studied this question.
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