Linking Cortical Morphometry in Self-Limited Epilepsy With Centrotemporal Spikes to Cognition, Function, and Molecular Architecture.

Siqi Yang; Jie Xia; Wei Liao; Yimin Zhou; Chengzong Peng; Yì Wáng; Zhiqiang Zhang

doi:10.1002/cns.70794

February 1, 2026

Linking Cortical Morphometry in Self-Limited Epilepsy With Centrotemporal Spikes to Cognition, Function, and Molecular Architecture.

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Key Points

The aim is to explore the relationship between neuroanatomical features in epilepsy and their behavioral and molecular associations.
Analyzed cortical morphometry in patients with epilepsy
Examined the relationship with centrotemporal spikes
Investigated cognitive function and molecular characteristics
Identified neuroanatomical heterogeneity in epilepsy
Established links between cortical features and cognitive performance
Found correlations with molecular architecture

Implication

Links cortical morphometry and molecular architecture to cognitive function in epilepsy, suggesting new insights into brain structure.

Abstract

Collectively, this study provides a novel framework for elucidating the neuroanatomical heterogeneity of epilepsy, offering insights into its behavioral and molecular correlates.

Discussion

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Cite This Study

Yang et al. (2026) studied this question.

synapsesocial.com/papers/699e918df5123be5ed04f32f https://doi.org/10.1002/cns.70794

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