Functional connectivity in self‐limited epilepsy with centrotemporal spikes increases with epilepsy duration and interictal spike exposure

Key Points

• The study aims to investigate the relationship between spike exposure duration and functional connectivity in epilepsy.
• Analyzed functional connectivity patterns in epilepsy patients
• Measured duration of interictal spike exposure
• Examined changes over time related to spike frequency
• Functional connectivity increases with longer spike exposure
• Prolonged exposure to spikes correlates with greater neural network alterations
• Spikes may serve as a target for preventing cognitive decline