Why the study?
Does combustible-tobacco or ENDS use affect CVD incidence compared to other tobacco statuses?
Does combustible-tobacco or ENDS use affect CVD incidence compared to other tobacco statuses?
This analysis of the PATH study found no significant difference in incident cardiovascular disease based on tobacco or ENDS use status over the studied intervals.
Null finding on tobacco/ENDS status and CVD incidence; leaves open causal effects and needs longer prospective confirmation.
This study found no difference in CVD incidence by tobacco status over three 3 year intervals, even for tobacco quitters. It is possible that additional waves of PATH Study data, combined with information from other large longitudinal cohorts with careful tracking of ENDS use patterns may help to further clarify this relationship.
No takes yet. Share an insight, caveat, or question.
Mahoney et al. (2022) studied this question.
Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context: