Functional analysis shows altered miR-199a-3p expression in tumor endothelial cells, indicating implications for tumor growth and metastasis.
Tumor endothelial cells (TECs) play a key role in tumor growth and metastasis. They exhibit distinct phenotypic and functional features compared with normal endothelial cells (NECs). Although microRNAs (miRNAs) play diverse roles in tumor progression, the differences in the miRNA expression profiles between TECs and NECs and their role in the TEC phenotype remain unclear.
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Hong et al. (2026) studied this question.
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