Focused on creating asymmetric structures with a chiral axis.
Targeted the synthesis of biologically relevant molecules.
Successfully synthesized various atropisomeric biaryls and heterobiaryls.
Demonstrated high enantioselectivity in the synthesis process.
Showed potential applications for newly synthesized compounds in catalysis.
Abstract
Atropisomeric architectures with a chiral axis are prevalent in biologically active molecules and natural products, and they are widely put to use in privileged catalysts and chiral ligands. Axially chiral...