Sex Differences in Outcomes of Complex Percutaneous Coronary Interventions Assisted With Mechanical Circulatory Support Devices

Women undergoing complex PCI with MCS support experienced higher procedural risk and worse early outcomes, yet adjusted 1-year MACE rates were comparable to men. The marked absolute differences in bleeding and mortality highlight the need for sex-specific approaches to patient selection, procedural planning, and post-PCI management in this high-risk population.