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The study aimed to evaluate measles immunity among adult blood donors in southern Italy to identify patterns of sero-susceptibility.

February 27, 2026

Immunity gap for measles in young adults: Seroprevalence study in blood donors in southern Italy.

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The study aimed to evaluate measles immunity among adult blood donors in southern Italy to identify patterns of sero-susceptibility.
Conducted a retrospective seroprevalence study using sera from 1579 healthy blood donors aged 18 to 65.
Measured anti-measles virus IgG antibodies using the ELISA test.
Performed statistical analyses to assess associations between sero-susceptibility and demographic factors.
Overall seroprevalence of anti-MV IgG was 85.3%.
Sero-susceptibility varied by age: 39.8% in individuals aged 18-24 years and 4.0% in the 45-54 age group.
77.2% of sero-susceptible individuals under 35 had received two doses of the measles vaccine.

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Retrospective seroprevalence study evaluates measles immunity in adult blood donors, indicating a need for public health action.

Centrone et al. (2026) studied this question.

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