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March 8, 2026EurosurveillanceOpen Access

Cross-sectional seroprevalence study of measles antibodies among children to identify gaps in population immunity, Ireland, 2024

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Authors

MBMelissa BradyHealth Service ExecutiveLBLieke BrouwerHealth Service ExecutiveKBKatie O’ BrienHealth Service Executive

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Overview

Cross-sectional study found 90.3% measles IgG seroprevalence in children, indicating gaps in immunity for older age groups.

Key Points

  • To determine the seroprevalence of measles IgG antibodies among children in Ireland.
  • Conducted a cross-sectional seroprevalence study from February to June 2024.
  • Utilized convenience sampling of anonymised residual serum samples from four hospital laboratories.
  • Tested samples for measles IgG antibodies using a chemiluminescence immunoassay.
  • Adjusted seropositivity rates for test sensitivity and specificity.
  • Out of 2,924 samples, 2,509 were seropositive, indicating a seroprevalence of 90.3%.
  • Higher seropositivity observed in ages 3-9 years compared to 10-17 years.
  • Children aged 3-5 years had 94.9% seropositivity and those aged 10-13 years had 89.1%.
  • Suboptimal immunity (< 95%) was found among children aged 10-17 years.

Cite This Study

Brady et al. (2026) studied this question.

synapsesocial.com/papers/69acc57d32b0ef16a404fccahttps://doi.org/10.2807/1560-7917.es.2026.31.9.2500313
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