Vertical 11.7 T MRI systems provide fast, high-resolution imaging of cardiac function in mouse models, improving upon lower field horizontal systems.
May expedite rodent cardiac phenotyping; leaves open translation of vertical-bore high-field MRI to clinical use.
This work shows that MR systems with a vertical bore design can be used to accurately measure cardiac function in both normal and chronically failing mouse hearts within one hour. The increased signal-to-noise ratio (SNR) due to the higher field strength could be exploited to obtain higher temporal and spatial resolution compared to previous studies that were performed on horizontal systems with lower field strengths.
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Schneider et al. (2003) studied this question.
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