Electrical Remodeling of the Atria Following Loss of Atrioventricular Synchrony
Why the study?
Does VVI pacing compared with AV sequential pacing cause atrial electrical remodeling and increase the incidence of atrial fibrillation?
Population
Patients undergoing VVI pacing
Comparison
VVI pacing (loss of AV synchrony) vs AV sequential pacing (DDD pacing)
Follow-up
Long-term
Authors
Discussion
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Member takes
Implication
May partly explain higher AF rates with VVI pacing; leaves open whether restoring AV synchrony improves clinical outcomes.
Structured PICO
Does VVI pacing compared with AV sequential pacing cause atrial electrical remodeling and increase the incidence of atrial fibrillation?
P
Population
Patients undergoing VVI pacing
I
Intervention
VVI pacing (loss of AV synchrony)
C
Comparator
AV sequential pacing (DDD pacing)
O
Outcome
Atrial electrical remodelingsurrogate
Loss of AV synchrony from VVI pacing causes reversible atrial electrical remodeling, potentially explaining the higher incidence of atrial fibrillation compared to AV sequential pacing.
Cite This Study
Sparks et al. (1999) studied this question.