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August 12, 2000BMJ2,160 citationsOpen Access

Association of systolic blood pressure with macrovascular and microvascular complications of type 2 diabetes (UKPDS 36): prospective observational study

AAAmanda Adler

Structured PICO

Does lower systolic blood pressure reduce macrovascular and microvascular complications in patients with type 2 diabetes?

P
Population
Patients with type 2 diabetes
I
Intervention
Systolic blood pressure levels (exposure)
O
Outcome
Macrovascular and microvascular complicationscomposite

In patients with type 2 diabetes, lower systolic blood pressure (especially <120 mm Hg) is associated with a reduced risk of macrovascular and microvascular complications.

Abstract

In patients with type 2 diabetes the risk of diabetic complications was strongly associated with raised blood pressure. Any reduction in blood pressure is likely to reduce the risk of complications, with the lowest risk being in those with systolic blood pressure less than 120 mm Hg.

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Amanda Adler (2000) studied this question.

synapsesocial.com/papers/69a1cf185eb5690d3d7148ebhttps://doi.org/10.1136/bmj.321.7258.412
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