Key result
Exercise training reduces DBP by ~1.3 mmHg with minimal SBP impact in adults with diabetes.
Why the study?
With the increasing prevalence of diabetes globally, there is an urgent need to assess the impact of exercise intervention on blood pressure reduction in diabetic patients.
Does exercise intervention reduce systolic and diastolic blood pressure in patients with diabetes?
Meta-Analysis (n=1,112)
Does exercise intervention reduce systolic and diastolic blood pressure in patients with diabetes?
Effect estimate: SMD -0.12 mmHg for SBP (95% CI -0.58 to 0.35, p < 0.0001); SMD -1.29 mmHg for DBP (95% CI -2.49 to -0.08, p < 0.0001) (95% CI SBP 95% CI -0.58 to 0.35; DBP 95% CI -2.49 to -0.08)
p-value: p=<0.0001
Structured exercise interventions provide a statistically significant reduction in both systolic and diastolic blood pressure in patients with diabetes.
Supports exercise for BP control in diabetes; confirms prior evidence on lifestyle cardiovascular benefits.
Diabetes is a disease that occurs when the blood glucose is too high in the body. The disease has become a deadly epidemic due to its widespread and increasing prevalence. With the increasing prevalence of diabetic cases globally, and most especially in the United States of America, there is an urgent need to manage the disease by assessing the impact of exercise on blood pressure reduction in a diabetic patient. An electronic search was conducted in PubMed and Google Scholar for studies published between January 2005 and December 2023. The meta-analysis was performed without any restriction on patients’ gender, demographics, and ethnicity. The finding was reported following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines (PRISMA) checklist. Six studies met the inclusion criteria for meta-analysis. Our result showed that the intervention group significantly caused a reduction in systolic blood pressure (SMD = -0.12 mmHg, 95% CI, -0.58 to 0.35; tau square = 0.3790; p < 0.0001) and diastolic blood pressure (SMD = -1.29 mmHg, 95% CI, -2.49 to -0.08; tau square = 2.9214; p < 0.0001) in patients with diabetes. The review demonstrated that regular exercise could positively impact patient health status and reduce the risk of death.
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Adekunle et al. (2026) conducted a meta-analysis in Adults with diabetes mellitus (type 2) with a mean age 53.4-61.8 years (n=1,112). Exercise training (aerobic, resistance, or combined) vs. Control (dietary recommendations, standard care, habitual activities, light stretching exercise) was evaluated on Change in systolic blood pressure (SBP) and diastolic blood pressure (DBP) levels (SMD -0.12 mmHg for SBP (95% CI -0.58 to 0.35, p < 0.0001); SMD -1.29 mmHg for DBP (95% CI -2.49 to -0.08, p < 0.0001), 95% CI SBP 95% CI -0.58 to 0.35; DBP 95% CI -2.49 to -0.08, p=<0.0001). Exercise training reduced diastolic blood pressure by 1.29 mmHg and systolic blood pressure by 0.12 mmHg compared to control in adults with diabetes.
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