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February 28, 2026American Journal of OphthalmologyOpen Access

Clinical Characteristics and Outcomes in Central Serous Chorioretinopathy with Subretinal Hyper-Reflective Material: MICRoN report 6

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Authors

NSNiroj Kumar SahooNHNasiq HasanNJNinan Jacob

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Overview

Retrospective cohort study evaluates visual outcomes in chronic central serous chorioretinopathy, suggesting significant complications in subretinal hyperreflective material cases.

Key Points

  • This study aims to assess the clinical characteristics and long-term visual outcomes of chronic central serous chorioretinopathy with subretinal hyperreflective material.
  • Conducted a retrospective multicenter cohort study from the Macula Society CSCR Study Group.
  • Included consecutive patients diagnosed with CSCR, both with and without SHRM.
  • Compared best-recorded visual acuity and imaging parameters between SHRM and non-SHRM groups.
  • The SHRM group had poorer baseline visual acuity compared to the non-SHRM group (p = 0.006).
  • SHRM eyes showed greater alterations in retinal pigment epithelium and higher rates of neurosensory retinal detachment.
  • Persistent subretinal fluid and photoreceptor irregularities were significantly higher in the SHRM group.

Cite This Study

Sahoo et al. (2026) studied this question.

synapsesocial.com/papers/69a286b80a974eb0d3c01efbhttps://doi.org/10.1016/j.ajo.2026.02.037
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Also Consider

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  1. 1Subretinal exudative deposits in central serous chorioretinopathy.1993 · 101 citations
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  4. 4Subretinal hyperreflective material in central serous chorioretinopathy2019 · 24 citations