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March 5, 2026Open Access

Demography, Clinical Characteristics and Long-Term Outcomes of Central Serous Chorioretinopathy in Women. MICRoN report number Fourteen.

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Authors

GGGiulia GregoriMarche Polytechnic UniversityNSNiroj Kumar SahooNHNasiq HasanUniversity of Pittsburgh

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Implication

Retrospective cohort study evaluates visual outcomes in women with CSCR, suggesting better prognosis compared to men.

Key Points

  • The study aims to compare the characteristics and long-term outcomes of chronic central serous chorioretinopathy between women and an age-matched cohort of men.
  • Conducted a multicenter retrospective cohort study
  • Included 426 eyes from women and men diagnosed with CSCR
  • Analyzed baseline and final best-recorded visual acuity (BRVA)
  • Assessed multimodal imaging parameters such as RPE alterations and subretinal fluid persistence
  • Used regression analysis to identify predictors of final visual acuity
  • Women had better BRVA at presentation compared to men (0.25 vs 0.31 logMAR; p=0.05)
  • Women exhibited smaller areas of RPE alterations (2.37 vs 1.59 disc areas; p=0.003)
  • Higher rates of complete SRF resolution were observed in women (p=0.001)
  • Men showed significantly more persistent SRF and recurrences (p=0.006 and p=0.02, respectively)
  • Logistic regression found persistent SRF linked to male gender and complex CSCR.

Cite This Study

Gregori et al. (2026) studied this question.

synapsesocial.com/papers/69a91df9d6127c7a504c1618https://doi.org/10.48620/95912
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Clinical Characteristics and Outcomes in Central Serous Chorioretinopathy with Subretinal Hyper-Reflective Material: MICRoN report 6.2026
  2. 2Clinical Characteristics and Outcomes in Central Serous Chorioretinopathy With Subretinal Hyper-Reflective Material: MICRoN Report 62026 · 1 citations
  3. 3Clinical variations and outcomes of central serous chorioretinopathy in Black and White patients: MICRoN report-16.2026
  4. 4Clinical variations and outcomes of central serous chorioretinopathy in Black and White patients: MICRoN report-162026
  5. 5Longitudinal structural changes in central serous chorioretinopathy: A multimodal imaging-based study2024 · 5 citations