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The study aims to evaluate survival outcomes and the influencing factors in pediatric acute myeloid leukemia patients.

February 28, 2026Annals of HematologyOpen Access

Treatment Outcomes and Factors Affecting Survival in Pediatric Acute Myeloid Leukemia

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The study aims to evaluate survival outcomes and the influencing factors in pediatric acute myeloid leukemia patients.
Retrospective evaluation of pediatric AML patients under 18 years from eastern Turkey between 2010 and 2023.
Application of the AML-BFM 2004 and AML-BFM 2012 treatment protocols.
Determination of risk groups based on chemotherapy response and genetic results.
Survival analyses using the Kaplan-Meier method and Cox regression analyses.
81.6% of patients achieved complete remission after induction therapy.
Overall mortality in patients was 38.8%, with higher rates in younger patients and those over 14 years.
Five-year survival rates were significantly higher for AML-M3 patients at 94% compared to 43% for non-AML-M3 patients.
Lower survival was associated with high leukocyte counts, low hemoglobin levels, and poor induction response.

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Examines survival outcomes in pediatric acute myeloid leukemia, indicating critical factors influencing prognosis.

Öncül et al. (2026) studied this question.

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