Retrospective analysis identifies White Blood Cell count and age as key prognostic factors in childhood acute lymphoblastic leukemia outcomes.
Key Points
To identify prognostic factors influencing relapse and survival in children with acute lymphoblastic leukemia treated with the ALL-BFM IC 2009 protocol.
Conducted a retrospective analysis of data from children diagnosed with acute lymphoblastic leukemia.
Included patients treated from January 2016 to January 2025 who completed induction chemotherapy.
Analyzed the impact of clinical factors such as age and white blood cell count on outcomes.
17.7% of patients experienced relapse and 9.7% died during the follow-up period.
5-year overall survival rate was 88.3% and event-free survival rate was 84.4%.
Age ≥6 years and white blood cell count >100,000/mm³ emerged as significant predictors of relapse.