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July 2, 2026Iraqi Journal of HematologyOpen Access

Clinical characteristics and outcome of pediatric patients diagnosed with acute lymphoblastic leukemia over 6 years’ period, single institute experience (Children Welfare Teaching Hospital)

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Authors

RARaghad Majid Al-SaeedHHHebatallah Ali Hussein

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Overview

Retrospective analysis evaluates outcomes of pediatric patients with acute lymphoblastic leukemia, indicating treatment effectiveness.

Key Points

  • This study aims to analyze the clinical characteristics and outcomes of pediatric patients diagnosed with acute lymphoblastic leukemia.
  • Retrospective analytic study over 6 years (January 1, 2017 - December 31, 2022)
  • Involved 329 newly diagnosed pediatric patients, excluding 257 cases
  • Examined demographics, treatment protocols (UKALL 2011 and UKALL 2019), and outcomes from electronic files.
  • Induction remission achieved in 296 patients (90%); induction failure in 18 patients (5.5%), and induction deaths in 15 patients (4.6%)
  • Overall survival at 5 years was 54.9%; event-free survival at 5 years was 52.2%
  • Steroid responsiveness correlates with good prognostic factors, with high-dose methotrexate protocol outperforming Capizzi.

Cite This Study

Al-Saeed et al. (2026) studied this question.

synapsesocial.com/papers/6a4600a29ed1343031310b16https://doi.org/10.4103/ijh.ijh_151_25
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Also Consider

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  1. 1Outcomes of children treated for relapsed or refractory acute lymphoblastic leukemia: A single tertiary care center experience2024 · 3 citations
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  3. 3Treatment Outcome of Children with Acute Lymphoblastic Leukemia According to Risk-Group Stratification: A Single Institution Experience2026
  4. 4Low Relapse Rate in Children With Acute Lymphoblastic Leukemia After Risk-Directed Therapy2001 · 23 citations
  5. 5Survival of Children with Acute Lymphoblastic Leukemia with Risk Group-Based Protocol Changes: A Single Center Experience with 460 Patients over a 20-Year Period2024