What question did this study set out to answer?

The research aims to investigate the circadian rhythm of melatonin receptors and their regulatory effect on clock gene expression in chick liver under different light conditions.

February 28, 2026Poultry ScienceOpen Access

Circadian rhythm of melatonin receptors under monochromatic light and their regulatory effect on clock genes in the chick liver

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Authors

LLLei LiuSecond Hospital of Shandong University NJNan JiangQingdao Agricultural University ZWZixu WangChina Agricultural University

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Implication

Demonstrates how melatonin receptors regulate clock genes in chick liver, highlighting the impact of monochromatic light.

Key Points

The research aims to investigate the circadian rhythm of melatonin receptors and their regulatory effect on clock gene expression in chick liver under different light conditions.
144 newly hatched chicks were divided into sham-operation and pinealectomy groups.
Chicks were exposed to white, red, green, and blue light for two weeks.
Liver samples were collected at six time points for analysis.
mRNA and protein expression of melatonin receptors and clock genes were assessed using qPCR and western blot.
Mel1a and Mel1b receptors showed a significant circadian rhythm affected by light wavelength.
Pinealectomy reduced the rhythmic expression of melatonin receptors.
Activation of Mel1a and RORα increased expression of seven clock genes, while Mel1b and Mel1c induced five clock genes.
Melatonin influenced the rhythm of cBmal1 and cPer2 in long-term cultured hepatocytes.

Cite This Study

Liu et al. (2026) studied this question.

synapsesocial.com/papers/69a287010a974eb0d3c02698 https://doi.org/10.1016/j.psj.2026.106712

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Circadian rhythm of melatonin receptors under monochromatic light and their regulatory effect on clock genes in the chick liver

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Key Points

Cite This Study

Circadian rhythm of melatonin receptors under monochromatic light and their regulatory effect on clock genes in the chick liver

Discussion

Member takes

Implication

Key Points

Cite This Study

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