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This study aims to evaluate the effectiveness of bronchoalveolar lavage cytology in diagnosing interstitial lung diseases.

February 28, 2026Journal of CytologyOpen Access

Role of Bronchoalveolar Lavage in Interstitial Lung Disease Diagnosis: A Cytological Perspective

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This study aims to evaluate the effectiveness of bronchoalveolar lavage cytology in diagnosing interstitial lung diseases.
Conducted an observational study with 100 ILD patients over a year.
Enrolled 31 patients requiring multidisciplinary diagnosis for ILD.
Processed bronchoalveolar lavage fluid using cytocentrifugation and staining techniques.
Assessed differential cell counts in BAL fluid.
Performed endobronchial biopsy and ultrasound-guided aspiration in select cases.
Mean age of patients was 41.2 years, with a majority being female.
Common ILD subtypes included sarcoidosis, CTD-ILD, idiopathic nonspecific interstitial pneumonia, and hypersensitivity pneumonitis.
BAL showed lymphocytosis in sarcoidosis (41.8%) and chronic hypersensitivity pneumonitis (56.7%).
Neutrophilia was also observed in some cases, not necessarily indicating infection.
BAL findings aligned with final diagnoses, supporting bronchoalveolar lavage's predictive value.

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Observational study evaluates bronchoalveolar lavage cytology in diagnosing interstitial lung disease, suggesting its diagnostic value.

Chachra et al. (2026) studied this question.

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