Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy shows retinal vessel dysfunction, suggesting links to retinal health.
Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL), the most common inherited cerebral small vessel disease (cSVD), involves NOTCH3-mediated microvascular pathology. As retinal health remains underexplored, serial ultra-widefield fluorescein angiography (UW-FA) was used to characterize dynamic vessel dysfunction.
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Serlin et al. (2026) studied this question.
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