Case series reports treatment efficacy and health care impacts of cannabinoid hyperemesis syndrome in adolescents, suggesting better diagnostic awareness is needed.
Cannabinoid hyperemesis syndrome (CHS), a recurring vomiting disorder triggered by long-term, frequent cannabis use, remains underdiagnosed and often leads to unnecessary diagnostic evaluations, increased health care utilization, and mental health burden. We present a large case series of CHS in pediatrics that includes data on treatment efficacy, health care utilization, and comorbidities.
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Castellvi et al. (2026) studied this question.
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