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February 28, 2026Tissue Engineering Part A

Adhesive Hydrogel Inks with Boronic Acid-Cis-Diol Complexation for On-Muscle Printing

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Authors

JLJ. S. LeeInstitute for Basic ScienceSLSumin LeeSungkyunkwan UniversitySLSeung Hyun LeeSungkyunkwan University

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Overview

Findings demonstrate improved tissue adhesion and cell behavior in bioadhesive hydrogel inks for muscle injuries.

Key Points

  • This research aims to develop a bioadhesive hydrogel ink that can effectively print on muscle tissues for better injury treatment.
  • Developed a hydrogel ink (PBAink) using alginate, phenylborate, and methacrylate.
  • Optimized salt concentration in buffer solutions to enhance the ink's properties.
  • Conducted 3D printing tests to evaluate tissue adhesion and structural stability.
  • PBAink showed a storage modulus similar to muscle tissue.
  • Demonstrated improved tissue adhesion compared to conventional inks.
  • Induced cell clustering and enhanced cell density on the printed scaffolds.

Cite This Study

Lee et al. (2026) studied this question.

synapsesocial.com/papers/69a287b00a974eb0d3c038d9https://doi.org/10.1177/19373341261417295
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