What does this research mean for the field?

The alginate–aminophenylboronic acid (Alg-APBA) hydrogel adhesive exhibits superior mechanical performance and biocompatibility compared to commercial fibrin adhesives, making it suitable for soft tissue fixation. Novelty: ClaimNovelty.NOVEL_FINDING. Consensus alignment: ConsensusAlignment.NEUTRAL.

What question did this study set out to answer?

The aim is to develop a novel hydrogel adhesive that does not require crosslinkers and has improved mechanical properties for tissue fixation.

March 3, 2026Open Access

Crosslinker-Free, Printable Alginate–Boronic Acid Hydrogel Adhesive with Enhanced Mechanical Performance for Soft Tissue Fixation

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Authors

AMAnna MarszałekAGH University of Krakow ZKZuzanna KurzępaAGH University of Krakow MGMikołaj GąbkaAGH University of Krakow

Discussion

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Implication

Presents a new hydrogel adhesive that enhances mechanical performance in soft tissue fixation, suggesting effective alternatives to sutures.

Key Points

The aim is to develop a novel hydrogel adhesive that does not require crosslinkers and has improved mechanical properties for tissue fixation.
Synthesis and characterisation of an alginate–aminophenylboronic acid hydrogel adhesive.
Conducted rheological analysis to assess shear-thinning and self-healing properties.
Performed mechanical testing to evaluate shear strength and interfacial toughness.
Assessed biocompatibility through in vitro tests with keratinocytes and fibroblast cells.
Achieved a shear strength of 19.0 ± 0.5 kPa and an interfacial toughness of 58.0 ± 2.11 J/m2.
The hydrogel adhesive maintained stability after one week in an acidic environment.
Demonstrated a high print fidelity with a print ratio of 0.99 ± 0.08, suitable for bioprinting.

Cite This Study

Marszałek et al. (2026) studied this question.

synapsesocial.com/papers/69a67eb2f353c071a6f0a0b8 https://doi.org/10.3390/molecules31050829

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March 3, 2026Open Access

Crosslinker-Free, Printable Alginate–Boronic Acid Hydrogel Adhesive with Enhanced Mechanical Performance for Soft Tissue Fixation

View Full Paper

Ask AI

Bookmark

Authors

AMAnna MarszałekAGH University of Krakow ZKZuzanna KurzępaAGH University of Krakow MGMikołaj GąbkaAGH University of Krakow

Discussion

Member takes

Implication

Presents a new hydrogel adhesive that enhances mechanical performance in soft tissue fixation, suggesting effective alternatives to sutures.

Key Points

The aim is to develop a novel hydrogel adhesive that does not require crosslinkers and has improved mechanical properties for tissue fixation.
Synthesis and characterisation of an alginate–aminophenylboronic acid hydrogel adhesive.
Conducted rheological analysis to assess shear-thinning and self-healing properties.
Performed mechanical testing to evaluate shear strength and interfacial toughness.
Assessed biocompatibility through in vitro tests with keratinocytes and fibroblast cells.
Achieved a shear strength of 19.0 ± 0.5 kPa and an interfacial toughness of 58.0 ± 2.11 J/m2.
The hydrogel adhesive maintained stability after one week in an acidic environment.
Demonstrated a high print fidelity with a print ratio of 0.99 ± 0.08, suitable for bioprinting.

Cite This Study

Marszałek et al. (2026) studied this question.

synapsesocial.com/papers/69a67eb2f353c071a6f0a0b8 https://doi.org/10.3390/molecules31050829

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Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

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